Group Publications

Journal articles

  1. Allerkamp HH, Leighton S, Pole T, Clark AR, James JL. Synergistic regulation of uterine radial artery adaptation to pregnancy by paracrine and hemodynamic factors. American Journal of Physiology-Heart and Circulatory Physiology. 2023 325(4):H790-805.

  2. Chappell, J, Aughwane, R, Clark, AR, Ourselin, S, David, AL, Melbourne, A. A review of feto-placental vascular flow modelling. Placenta. 2023 142:56-63.

  3. Clark, AR, Chernyavsky, IL, Jensen, OE. The complexities of the human placenta.Physics Today. 2023 76(4):26.

  4. Lee, TC, Moulvi, A, James, JL, Clark, AR. Multi-scale Modelling of Shear Stress on the Syncytiotrophoblast: Could Maternal Blood Flow Impact Placental Function Across Gestation?. Annals of Biomedical Engineering. 2023 51(6):1256-1269.

  5. May, R, Maso Talo, G, Clark, AR, Mynard, J, Smolich, J, Blanco, P, Müller, L, Gentles, T, Bloomfield, F, Safaei, S. From Fetus to Neonate: A Roadmap for Cardiovascular Modelling in Early Life. WIREs Mechanisms of Disease. 2023 31:e1608.

  6. Allerkamp HH, Pole T, Boukham A, James JL, Clark AR. Pregnancy-specific uterine vascular reactivity: a data-driven computational model of shear-dependent, myogenic, and mechanical radial artery features. American Journal of Physiology-Heart and Circulatory Physiology. 2022 323(1):H72-88.

  7. Clark A, Flouri D, Mufti N, James J, Clements E, Aughwane R, Aertsen M, David A, Melbourne A. Developments in functional imaging of the placenta. The British Journal of Radiology. 2023 Jun;96(1147):20211010.

  8. Clark AR, Yoshida K, Oyen ML. Computational modeling in pregnancy biomechanics research. Journal of the Mechanical Behavior of Biomedical Materials. 2022 Apr 1;128:105099.

  9. James JL, Boss AL, Sun C, Allerkamp HH, Clark AR. From stem cells to spiral arteries: A journey through early placental development. Placenta. 2022 Jul 1;125:68-77.

  10. James JL, Tongpob Y, Srinivasan V, Crew RC, Bappoo N, Doyle B, Gerneke D, Clark AR, Wyrwoll CS. Three-dimensional visualisation of the feto-placental vasculature in humans and rodents. Placenta. 2021 Oct 1;114:8-13.

  11. Srinivasan V, Melbourne A, Oyston C, James JL, Clark AR. Multiscale and multimodal imaging of utero-placental anatomy and function in pregnancy. Placenta. 2021 Sep 1;112:111-22.

  12. Byrne M, Aughwane R, James JL, Hutchinson JC, Arthurs OJ, Sebire NJ, Ourselin S, David AL, Melbourne A, Clark AR. Structure-function relationships in the feto-placental circulation from in silico interpretation of micro-CT vascular structures. Journal of theoretical biology. 2021 May 21;517:110630.

  13. Clark AR, Lee TC, James JL. Computational modeling of the interactions between the maternal and fetal circulations in human pregnancy. WIREs Mechanisms of Disease. 2021 Jan;13(1):e1502.

  14. Sun C, Groom KM, Oyston C, Chamley LW, Clark AR, James JL. The placenta in fetal growth restriction: what is going wrong?. Placenta. 2020 Jul 1;96:10-8.

  15. Saghian R, Bogle G, James JL, Clark AR. Establishment of maternal blood supply to the placenta: insights into plugging, unplugging and trophoblast behaviour from an agent-based model. Interface Focus. 2019 Oct 6;9(5):20190019.

  16. Tun WM, Yap CH, Saw SN, James JL, Clark AR. Differences in placental capillary shear stress in fetal growth restriction may affect endothelial cell function and vascular network formation. Scientific Reports. 2019 Jul 8;9(1):9876.

  17. Saw SN, Tay JJ, Poh YW, Yang L, Tan WC, Tan LK, Clark A, Biswas A, Mattar CN, Yap CH. Altered placental chorionic arterial biomechanical properties during intrauterine growth restriction. Scientific reports. 2018 Nov 8;8(1):16526.

  18. James JL, Saghian R, Perwick R, Clark AR. Trophoblast plugs: impact on utero-placental haemodynamics and spiral artery remodelling. Human Reproduction. 2018 Aug 1;33(8):1430-41.

  19. Clark AR, James JL, Stevenson GN, Collins SL. Understanding abnormal uterine artery Doppler waveforms: a novel computational model to explore potential causes within the utero-placental vasculature. Placenta. 2018 Jun 1;66:74-81.

  20. James JL, Chamley LW, Clark AR. Feeding your baby in utero: how the uteroplacental circulation impacts pregnancy. Physiology. 2017 May;32(3):234-45.

  21. Saghian R, James JL, Tawhai MH, Collins SL, Clark AR. Association of placental jets and mega-jets with reduced villous density. Journal of Biomechanical Engineering. 2017 May 1;139(5):051001.

  22. Clark AR, Kruger JA. Mathematical modeling of the female reproductive system: from oocyte to delivery. Wiley Interdisciplinary Reviews: Systems Biology and Medicine. 2017 Jan;9(1):e1353.

  23. Lin M, Mauroy B, James JL, Tawhai MH, Clark AR. A multiscale model of placental oxygen exchange: The effect of villous tree structure on exchange efficiency. Journal of theoretical biology. 2016 Nov 7;408:1-2.

  24. James J, Tun W, Clark A. Quantifying trophoblast migration: In vitro approaches to address in vivo situations. Cell Adhesion & Migration. 2016 Mar 3;10(1-2):77-87.

  25. Clark AR, Lin M, Tawhai M, Saghian R, James JL. Multiscale modelling of the feto–placental vasculature. Interface focus. 2015 Apr 6;5(2):20140078.

Student theses

Some student theses are available only to members of University of Auckland, but may be made available on request to those external to the University.

  1. Mary Spring, MSc, 2022, A Comparison of 2D and 3D Imaging Tools to Quantify Placental Structure in Normal and Growth-Restricted Pregnancies.

  2. Stephanie Leighton, ME, 2022, Computational modelling of what matters for uterine vascular network function.

  3. Jonathan Reshef, ME, 2021, 3D virtual reconstruction of the uterus.

  4. Izza Ismail, PhD, 2020, Cellular and molecular mechanisms of maternal immune response in early pregnancy.

  5. Teagan Pole, MSc, 2020, How do the uterine radial arteries adapt to pregnancy.

  6. Ali Moulvi, ME, 2020, The shear stress response of the syncytiotrophoblast.

  7. Win Min Tun, PhD, 2019, Shear stress and oxygen in placental vascular development.

  8. Monika Byrne, ME, 2019, Modelling Human Feto-Placental Circulation Based on Imaging.

  9. Rojan Saghian, PhD, 2018, Modelling the uterine circulation to understand the causes and consequences of inadequate spiral artery remodelling.

  10. Mabelle Lin, PhD, 2017, Multiscale modelling of blood flow and transport in the human placenta.